Dr. C.J. Tsai
Dr. C.J. Tsai
Professor and Eminent Scholar
Research Interests
phenylpropanoid metabolism
wood formation
one-carbon metabolism
functional genomics
metabolite profiling
bioinformatics
Research projects in my lab center around the theme of dissecting molecular mechanisms underpinning tree fitness and biomass productivity. I am particularly interested in the regulation of phenylpropanoid metabolism. Two classes of phenylpropanoids, phenolic glycosides and condensed tannins, in particular, play important roles in defense and stress management among Salicaceae (e.g., poplars and willows), and together with lignin, represent a large carbon sink that can account for more than 50% of leaf biomass in these species. Their potential effects on tree growth, fitness, and wood quality, and their documented impacts on ecosystem dynamics are the driving force behind this line of research into the molecular regulation of phenylpropanoid metabolism.
Publications
Qin, H; Feng, T; Harding, S; Tsai, C; and Zhang, S. 2008. An efficient method to identify differentially expressed genes in microarray experiments. Bioinformatics 24:1583-1589.
Luo, K; Harding, S; and Tsai, C. 2008. A modified T-vector for simplified assembly of hairpin RNAi constructs. Biotechnology Letters 30:1271-1274.
Oakley, R; Wang, Y; Ramakrishna, W; Harding, S; and Tsai, C. 2007. Differential expansion and expression of alpha- and beta-tubulin gene families in Populus. Plant Physiology 145:961-973.
Busov, V and Tsai, C. 2007. Perennial challenges and opportunities. New Phytologist 176:3-6.
Rajinikanth, M; Harding, S.A.; and Tsai, C. 2007. The glycine decarboxylase complex multienzyme family in Populus. Journal of Experimental Botany 58:1761-1770.
Lin, J; Gunter, L; Harding, S.A.; Kopp, R; McCord, R; Tsai, C; Tuskan, G; and Smart, L. 2007. Development of AFLP and RAPD markers linked to a locus associated with twisted growth in corkscrew willow (Salix matsudana ‘Tortuosa’). Tree Physiology 27:1575-1583.
Tiimonen, H; Häggman, H; Tsai, C; Chiang, V; and Aronen, T. 2007. The seasonal activity and the effect of mechanical bending and wounding on the PtCOMT promoter in Betula pendula Roth. Plant Cell Reports 26:1205-1214.
Grants
"A functional genomics approach to investigate regulation of phenolic glycoside metabolism in Populus", NSF, 07/01/2008-12/31/2010 $450000
"A genomics investigation of partitioning into and among flavonoid-derived condensed tannins for carbon sequestration in Populus", DOE, 08/15/2008-08/14/2010 $347265
"Post-translational regulation and transgenic manipulation of Populus alpha- and beta-tubulins during wood formation", CPBR, 01/01/2009-12/31/2010 $177000
Office:
Davison Life Sciences B314
Phone: 706.542.1271
Lab:
Davison Life Sciences B310
Phone: 706.542.1304